---
product_id: 258199059
title: "Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets"
brand: "life extension"
price: "₩52665"
currency: KRW
in_stock: true
reviews_count: 5
category: "Life Extension"
url: https://www.desertcart.kr/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain
store_origin: KR
region: South Korea
---

# 1700 mcg bioactive 5-MTHF folate Supports brain & cognitive health Maintains healthy homocysteine levels Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets

**Brand:** life extension
**Price:** ₩52665
**Availability:** ✅ In Stock

## Summary

> 💡 Elevate your heart and mind with every tablet — don’t miss out on optimized wellness!

## Quick Answers

- **What is this?** Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets by life extension
- **How much does it cost?** ₩52665 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.kr](https://www.desertcart.kr/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain)

## Best For

- life extension enthusiasts

## Why This Product

- Trusted life extension brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Pure & Clean Formula:** Non-GMO, gluten-free, vegetarian tablets crafted with premium ingredients
- • **Science-Backed Efficacy:** Formulated based on 40+ years of research for maximum bioavailability
- • **Daily Wellness Made Simple:** One tablet a day to effortlessly support your long-term health goals
- • **Dual Heart & Brain Support:** Clinically linked to maintaining cardiovascular and cognitive wellness
- • **Bioactive Folate Powerhouse:** 1700 mcg of 5-MTHF for up to 7x better absorption than folic acid

## Overview

Life Extension Optimized Folate delivers 1700 mcg of metabolically active L-Methylfolate (5-MTHF), a superior form of folate that supports healthy homocysteine levels linked to cardiovascular and cognitive health. This non-GMO, gluten-free, vegetarian supplement is designed for maximum absorption and efficacy, backed by over four decades of scientific research, making it an essential daily boost for proactive health-conscious professionals.

## Description

Folate helps maintain homocysteine levels within the normal range, which promotes cardiovascular health. And it also supports neurotransmitter synthesis — which in turn helps maintain cognitive abilities. However, not everyone has sufficient activity of the enzyme required to convert folate to its biologically active form, 5-methyltetrahydrofolate, or 5-MTHF. That’s why each vegetarian tablet of Optimized Folate provides 1,700 mcg of the bioactive 5-MTHF form of folate which is up to 7 times more bioavailable than ordinary folic acid

Review: It worked as intended, thanks!
Review: buena marca, hasta ahora todo muy bien

## Features

- BIOLOGICALLY ACTIVE FOLIC ACID — Our Optimized Folate formula promotes both cardiovascular and cognitive health with 1700 mcg of folate in the form of 5-MTHF (L-Methylfolate), the metabolically active form of folic acid.
- WHY FOLATE? – Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with heart and brain health. Folate, a B vitamin, helps maintain homocysteine levels already within normal range. However, not everyone can efficiently convert folate to its biologically active form. Our formula provides 5-MTHF, so you don’t have to.
- HEART & BRAIN-FRIENDLY NUTRIENT – Because folate helps inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular biomarker. Since healthy homocysteine levels have been associated with cognitive health, getting enough folate is especially crucial for individuals who want to maintain brain health.
- INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free, and manufactured in the USA—and a Certificate of Analysis is available for every product we produce.
- LIVE YOUR HEALTHIEST LIFE - For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. Our formulations are created using the ingredients and dosages used in the studies that inspired them, ensuring that maximum bioavailability and efficacy is achieved.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00UD0IPYU |
| ASIN  | B00UD0IPYU |
| Additives | microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid. |
| Age Range Description | Adult |
| Allergen Information | Gluten Free, Non-GMO |
| Best Sellers Rank | #11,926 in Health ( See Top 100 in Health ) #132 in Vitamin B Supplements |
| Brand | Life Extension |
| Customer Reviews | 4.7 4.7 out of 5 stars (3,676) |
| Customer reviews | 4.7 4.7 out of 5 stars (3,676) |
| Date First Available | 10 March 2014 |
| Format | Tablet |
| Is Discontinued By Manufacturer  | No |
| Item model number  | 01939 |
| Manufacturer  | Life Extension |
| Product Dimensions  | 5.31 x 5.31 x 9.47 cm; 49.9 g |
| Product Name | L-Methylfolate Supplement |
| Serving Recommendation | Take one (1) tablet daily |
| Units | 100 Count |
| Weight | 0.2 Kilograms |

## Product Details

- **Brand:** Life Extension
- **Diet type:** Gluten Free
- **Flavour:** Unflavored
- **Item form:** Tablet
- **Primary supplement type:** Folate as (6S)-5-Methyltetrahydrofolate, calcium salt

## Images

![Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets - Image 1](https://m.media-amazon.com/images/I/71vf+u6dkiL.jpg)

## Questions & Answers

**Q: It says 1700 mcf DFE of folate, but how of that is actual folic acid equivalent?**
A: Hello, We apologize for any confusion. At the end of August of 2020, we updated our Optimized Folate supplement facts section. The amount of folate was updated from 1,000 mcg to 1,700 mcg based on updated FDA labeling guidelines. This change is a result of what the FDA has defined as dietary folate equivalents (DFE). They determined that 0.6 mcg of (6S)-5-methyltetrahydrofolate, calcium salt is equal to 1 mcg DFE. They have also determined that one mcg of naturally occurring folate is equal to one mcg DFE. Their rationale is that this accounts for the greater bioavailability (6S)-5-methyltetrahydrofolate, calcium salt compared to naturally occurring folate. The change to 1,700 mcg in this product allows us to deliver the desired potency in terms of DFE.

**Q: What is the expiration date?**
A: The expiration date on mine is 7/20/2023, but I bought it over 3 months ago. I have no idea what the expiration date will be on the bottle you’re buying.

**Q: Is this Metafolin?**
A: Metafolin is a trademarked name for the active form of folate, known as methylfolate. While Optimized Folate doesn't utilize this specific brand, it does include L-Methylfolate.

**Q: Is any component of your usa manufactured  product sourced from china or india?**
A: It's been a very long time since I purchased this product. I no longer have the container and have consumed all of the product. That said, I have since switched to Folic Acid 800 mcg made in Austin Texas and available on Amazon.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by C***N on 5 February 2026*

It worked as intended, thanks!

### ⭐⭐⭐⭐⭐ Review
*by J***A on 20 October 2025*

buena marca, hasta ahora todo muy bien

### ⭐⭐⭐⭐⭐ Review
*by C***N on 15 September 2025*

Ya llevo tomándolo hace tiempo, es de muy buena calidad

## Frequently Bought Together

- Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets
- Life Extension TMG 500 mg – Trimethylglycine Supplement – Encourages Healthy Homocysteine Levels – Gluten-free – Non-gmo – Vegetarian – 60 Liquid Vegetarian Capsules
- Life Extension Neuro-Mag Magnesium L-Threonate, Magnesium L-threonate, Memory Health, Quick Thinking, Cognitive Health Support, Vegetarian, Non-GMO, 90 Vegetarian Capsules

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*Product available on Desertcart South Korea*
*Store origin: KR*
*Last updated: 2026-02-15*