--- product_id: 258595795 title: "SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood & Antioxidant Defense - 30 Servings" brand: "jarrow formulas" price: "₩103968" currency: KRW in_stock: true reviews_count: 5 category: "Jarrow Formulas" url: https://www.desertcart.kr/products/258595795-same-400-mg-30-tablets-highest-concentration-of-active-s store_origin: KR region: South Korea --- # Vegan & allergen-free formula 400 mg potent SAMe dose Enteric-coated for max bioavailability SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood & Antioxidant Defense - 30 Servings **Brand:** jarrow formulas **Price:** ₩103968 **Availability:** ✅ In Stock ## Summary > 💥 Elevate your wellness game with Jarrow’s powerhouse SAMe! ## Quick Answers - **What is this?** SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood & Antioxidant Defense - 30 Servings by jarrow formulas - **How much does it cost?** ₩103968 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.kr](https://www.desertcart.kr/products/258595795-same-400-mg-30-tablets-highest-concentration-of-active-s) ## Best For - jarrow formulas enthusiasts ## Why This Product - Trusted jarrow formulas brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Clean & Green Formula:** Vegan, gluten-free, and free from 9 major allergens - • **Triple-Action Wellness:** Supports joints, liver detox, and brain metabolism - • **Shielded for Absorption:** Enteric coating ensures active delivery where it counts - • **Power-Packed 400 mg SAMe:** Extra strength dose for daily vitality - • **30-Day Mood & Energy Boost:** One tablet a day to keep you sharp and balanced ## Overview Jarrow Formulas SAMe 400 mg delivers a high-potency, enteric-coated supplement designed to support joint health, liver function, brain metabolism, and mood balance. This vegan, allergen-free formula offers 30 servings per bottle, making it a clean, convenient daily boost for professionals seeking holistic vitality and mental clarity. ## Description Jarrow Formulas SAMe provides SAMe (S-Adenosyl Methionine), a naturally derived compound that plays a role in supporting various biochemical systems in the body. Each tablet of Jarrow Formulas SAMe provides 400 mg of SAMe to provide benefits. Jarrow Formulas SAMe offers a wide array of benefits that can support various aspects of your health and well-being. SAMe supports joint health, and liver function.* Jarrow Formulas SAMe is non-GMO, vegan-friendly, and gluten free, making it an ideal choice for those with dietary restrictions.* These tablets are also wheat free, soy free, dairy free, egg free, fish/shellfish free, peanut/nut free, and sesame free. Taking Jarrow Formulas SAMe is simple and convenient. Adults should take 1 tablet per day on an empty stomach or as directed by your qualified healthcare professional. At Jarrow Formulas, we aren't your typical vitamin company. We believe everyone has the right to feel good in their own body. Jarrow Formulas’ original goal has always remained the same: To design superior dietary supplements that help empower individuals to take charge of their own health. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Review: Me fascinan - Súper buenas, he notado el cambio que he tenido en el estado de ánimo y tengo mucho más energía, me hacen sentir muy bien Review: Contre le surmenage et les signes avant coureurs de la dépression - Super efficace , mon mari et moi avons retrouvés une vie. Nous avons fait une cure de 3 mois ensemble et aujourd'hui, nous sommes aussi efficaces qu'à notre première rencontre. Nos ados ne nous reconnaissent plus et notre entourage n'arrive pas à nous suivre ni au boulot ni club . ☺ ## Features - One (1) bottle of Jarrow Formulas SAMe 400 mg Extra Strength Vegan Naturally Derived SAMe Dietary Supplement, SAMe Supplement Supports Joint Health, Liver Health and Brain Health, for a 30-day supply - SAMe balanced mood support supplement formula provides 400 mg SAMe from 800 mg of SAMe tosylate disulfate and is enteric-coated to ensure a biologically active product - SAMe supports brain metabolism and the production of healthy connective tissue for joint support; SAMe metabolism supports glutathione synthesis for antioxidant and liver support - These brain supplements for memory are vegan, wheat free, gluten free, soy free, dairy free, egg free, fish free, shellfish free, peanut free, tree nut free and sesame free for an allergy friendly supplement - Suggested Use for SAMe supplement: Adults take 1 tablet a day on an empty stomach or as directed by your qualified healthcare professional ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0013OSJU0 | | Age Range Description | Adult | | Allergen Information | Dairy Free, Egg Free, Gluten Free, Soy Free, Wheat Free | | Best Sellers Rank | #42,524 in Health ( See Top 100 in Health ) #145 in Enzyme Nutritional Supplements | | Brand | Jarrow Formulas | | Brand Name | Jarrow Formulas | | Color | White | | Container Type | Bottle | | Customer Reviews | 4.4 out of 5 stars 2,062 Reviews | | Diet Type | Vegetarian | | Dosage Form | 400 mg | | Flavor | Unflavored | | Flavour | Unflavored | | Global Trade Identification Number | 00790011200208 | | Item Dimensions | 5.1 x 7.6 x 12.7 centimeters | | Item Form | Tablet | | Item Weight | 59 g | | Item form | Tablet | | Item weight | 59 g | | Manufacturer | Jarrow Formulas | | Manufacturer Part Number | P30525 | | Material Features | Dairy Free, Egg Free, GMO Free, Gluten Free, Nut Free, Shellfish Free, Vegan | | Model Name | SAMe 400 | | Model Number | P30525 | | Number of Items | 1 | | Primary Supplement Type | Vitamin | | Primary supplement type | Vitamin | | Product Benefits | Brain Health Support | | Special Ingredients | Amino Acid | | Specific Uses For Product | Laboratory | | Total Servings Per Container | 30 | | UPC | 790011200208 | | Unit Count | 30 Count | | Unit count | 30 Count | ## Product Details - **Brand:** Jarrow Formulas - **Flavour:** Unflavored - **Primary supplement type:** Vitamin - **Unit count:** 30 Count - **Item form:** Tablet - **Item weight:** 59 g - **Item dimensions L x W x H:** 5.1 x 7.6 x 12.7 centimeters - **Special ingredients:** Amino Acid - **Diet type:** Vegetarian - **Product benefits:** Brain Health Support ## Images ![SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood & Antioxidant Defense - 30 Servings - Image 1](https://m.media-amazon.com/images/I/711NpRr52JL.jpg) ## Questions & Answers **Q: Does this one hace mannitol in it?** A: I don't know why this has mannitol, but I suspect many who have GI reactions to this supplement are actually reacting to the mannitol, as it can be used as a laxative. I would test myself with a mild mannitol prep before buying a supplement containing mannitol, as you may have to discard an expensive supplement. **Q: Does anyone make a brand with no Mannitol and no Titanium dioxide with a butanedisulfonate form in enteric-coated tablets?** A: Yep, Azendus does and for a while now they've been the only company in the U.S. that has the patent to make the butanedisulfonate version after GNC's expired. Butanedisulfonate is the formula used in SAM-e clinical studies for treating depression. **Q: Other ingredients? Most supplements contain a lot of other ingredients besides the SAM-3 which I do NOT want to be exposed to. Ingredients, please?** A: Other Ingredients: Cellulose, silicon dioxide, glyceryl behenate, magnesium stearate (vegetable source), enteric coating (methacrylate copolymers), titanium dioxide, magnesium silicate, triethylcitrate, riboflavin, glycerol palmitostearate, medium chain triglycerides, carboxymethyl starch sodium salt and mannitol.Suitable for vegetarians/vegans. **Q: How come a month later I feel no effect whatsoever with any of the benefits it provides?** A: We recommend to discuss your health goals with your doctor and proceed with their guidance. Establishing the most effective dose may require trial and error, along with supervision, depending on your specific goals. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Me fascinan *by M***. on 10 May 2025* Súper buenas, he notado el cambio que he tenido en el estado de ánimo y tengo mucho más energía, me hacen sentir muy bien ### ⭐⭐⭐⭐⭐ Contre le surmenage et les signes avant coureurs de la dépression *by J***S on 19 February 2018* Super efficace , mon mari et moi avons retrouvés une vie. Nous avons fait une cure de 3 mois ensemble et aujourd'hui, nous sommes aussi efficaces qu'à notre première rencontre. Nos ados ne nous reconnaissent plus et notre entourage n'arrive pas à nous suivre ni au boulot ni club . ☺ ### ⭐⭐⭐⭐⭐ A Great Sam-E Supplement (but Your Mileage May Vary) *by C***5 on 15 October 2013* I've always battled mild'ish depression and mild-to-severe anxiety. Many supplements may help ease depression and anxiety, but it often comes at the cost of having side-effects (e.g. unusual bowel movements). Such is also the case with Sam-e as many folks report a counter-intuitive increase in paranoia and/or anxiety. As the popular saying goes, "your mileage may vary" as the effects of Sam-E vary based on each individual's internal chemistry. Three years ago, I started taking the Nature's Made brand (very commonly found at a local pharmacy) for a short period of time. Folks online reported that effective combating of depression required about 800mg to 1600mg per day in order to see an effect. I was on this regimen for about two weeks and became EXTREMELY PARANOID AND ANXIOUS about the most irrational of things. About a month ago, I re-researched into Sam-E again. New information and user testimonials had come out over the last few years about differences in brand effectiveness, daily dosage, etc. As I alluded to before, some folks may need a high dosage like 1600mg to see a difference. However, I noticed that I only need a fraction of that amount in order to feel better. I started off with Nature's Made and took about a much lower dosage at 400mg (200mg in the morning and 200mg in the afternoon). I felt great after the morning dosage, but the increase in anxiety crept up shortly after the afternoon dosage. No paranoia this time around though. This forced me to think about scaling the daily dosage back to 200mg per day (once in the morning only). After doing so, I started feeling great! Additionally, I have been taking my Sam-E with a B-Complex in the morning. Per Dr. Andrew Weil (which you can search online and read for yourself), he recommends the following to be used alongside Sam-E: "Take a daily multivitamin supplement that provides 400 mcg of folic acid, at least 50 mg of vitamin B6 and 50 mcg of B12 (along with the rest of the B-complex)." Many folks also recommend that you stay very hydrated as another means of helping Sam-E do its job. Here are my experiences: -- I definitely feel more alert throughout the day and have had a happier, more optimistic inclination about the day-to-day stuff in life. -- Similarly, I notice that I don't need as much coffee during the day. Before Sam-E, I needed at least a few (large) cups per day. Now, one cup of coffee in the morning is more than enough. -- I definitely feel as if I sleep better and have more drive to get out of bed in the mornings. Like the Chicken or the Egg argument, I'm sure that getting a more restful night's of sleep is also helping me feel better throughout the day. -- I used to constantly fall asleep during Movies and TV shows in the early evenings. Sam-E has given me an extra boost of energy where I don't prematurely fall asleep. -- Although many have said that Sam-E doesn't drastically help with their anxiety, I noticed that by taming depression, my anxiety has also been reduced. For example, I have felt an increase in confidence; the extra spark of energy has allowed me to give off a healthier vibe towards others (e.g. constant smile, better at holding eye contact, less stuttering/flustering). -- I have also felt motivated to complete my (often mundane) day-to-day tasks, such as cleaning the house, doing the dishes, cook dinner, etc. Similarly, at work, I have seen an increase in successfully meeting my daily responsibilities since taking Sam-E. The downside to Sam-E is that it can be very expensive and not covered by any insurance since it's a vitamin supplement. This forced me to research into cheaper options for Sam-E. Luckily, the Jarrow's brand is highly raved by other Amazon users AND the price is substantially less than buying the Nature's Made version at a local store. I have felt the same positive effects from Jarrow's as I did when using Nature's Made. The only thing to beware is that a few people have said that the effects ARE different between the two brands (both positive and negative) - again, your mileage my vary. Also, Sam-E isn't a "magic bullet" solution. Sam-E can only do so much if you're out of shape and/or are sleep deprived. For example, I am a late-night owl and if I only get a few hours of sleep, I wake up feeling groggy (just as any normal person would). You have to be realistic about Sam-E; it can enable you to feel better but the problem won't entirely go away unless you choose to make other lifestyle changes. *BEWARE OF THE PACKAGING/SHIPPING* The last thing I wanted to point out is to beware of the packaging. I ordered my Jarrow's 200mg directly from Amazon and the packaging was EXTREMELY POOR; the vitamins were stuffed into a small bubble mailer that was clearly not protected from getting "squished." When it arrived, the box inside was compressed into half its size (presumably from having other packages sit on top of it) AND it caused half of the blister packs to break open (leaving the vitamins exposed into the air). As other reviewers have mentioned, Sam-E is very sensitive to air/moisture changes, so I was forced to throw away any tablets that were already exposed. FYI, other vendors will put the vitamins into a small cardboard box stuffed with large air bubbles to protect the item from getting "squished." Granted, other vendors are more expensive but I'm also not throwing away wasted tablets. Although I won't dock stars away from the product (since it's not Jarrow's fault), it is absolutely something that buyers need to be aware of. Note: I am not a licensed clinical professional. Any information provided above is meant to be used for informational purposes only and should not replace the advice of an actual physician. ## Frequently Bought Together - Jarrow Formulas SAMe 400 mg, Supports Joint Health, Liver Function, Brain Metabolism, 30 Tablets, Up To a 30 Day Supply - Jarrow Formulas Magnesium L-Threonate, MagMind Magtein Brain Supplements for Memory Support, 90 Veggie Capsules, Up to a 30 Day Supply - Jarrow Formulas® SAMe 200 mg, Supports Joint Health, Liver Function, Brain Metabolism, 60 Tablets, Up To A 60 Day Supply --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.kr/products/258595795-same-400-mg-30-tablets-highest-concentration-of-active-s](https://www.desertcart.kr/products/258595795-same-400-mg-30-tablets-highest-concentration-of-active-s) --- *Product available on Desertcart South Korea* *Store origin: KR* *Last updated: 2026-08-19*