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🛡️ Say goodbye to itch, hello to calm skin—your daily defense against irritation!
E45 Itch Relief Cream is a dermatologist-tested, dual-action treatment formulated with 5% urea and 3% lauromacrogols to instantly soothe itching and skin irritation caused by eczema, dermatitis, and dry skin. Its fast-absorbing, non-greasy formula hydrates deeply while providing effective relief, trusted for over 60 years. Conveniently sized at 50g, it’s perfect for professional millennials seeking reliable, everyday skin comfort.












| ASIN | B01BKO8B4G |
| ASIN | B01BKO8B4G |
| Best Sellers Rank | 1,163 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 9 in Itching & Rash Treatments 10 in Skin Condition Remedies |
| Brand | E45 |
| Country of origin | United Kingdom |
| Customer Reviews | 4.5 4.5 out of 5 stars (1,838) |
| Customer reviews | 4.5 4.5 out of 5 stars (1,838) |
| Date First Available | 8 Feb. 2016 |
| Format | Cream |
| Item model number | 100694329 |
| Manufacturer | E45 |
| Manufacturer contact | MA holder: Crookes Healthcare Ltd, NG2 3AA, UK. Manufacturer: Reckitt Benckiser Healthcare (UK) Ltd, HU8 7DS. |
| Product Dimensions | 3.8 x 4.2 x 14.2 cm; 60 g |
| Storage Instructions | Store below 25°c. |
| Units | 50.0 gram |
| Weight | 50 g |
X**S
Fast absorbing cream for irritated skin
This cream spreads well and absorbs almost instantly, leaving the skin soft without any stickiness. It helps reduce that itchy, uncomfortable feeling and is gentle enough for frequent use. The 50 g size is convenient for carrying around.
A**L
Excellent
I have mild eczema, and try to steer clear of steroid creams after years of use. So I tried this product and found it to be great for mostursing and soothing some mild problem areas. Of course it's not as fast acting but it feels better for my skin. I love it.
P**R
Really good but leaves a smell
It's very good at relieving my super sensitive, dry, itchy skin. It love that it doesn't leave my skin greasy or clammy feeling. The only thing I don't like is the smell. I'm not sure if that is typical of E45 or some other ingredient in this formulation.
A**N
Very effective
As described. Very effective
S**.
E45 Itch Relief Cream.
Very good product, advised to get it by a local District Nurse for my Husbands as he felt itchy all the time due to ilness, he felt much better after rubbing it in the itchy areas. I will buy it again.
S**N
Very effective cream
Great product. Very effective. Good value.
T**D
E45 for itchy skin
Very good price this cream certainly eases itching in my cast my arm i personally need to use it 4 times a day right now
M**.
Very effective
Very effective
A**R
Excellent product for dermatitis
O**A
It came in before the delivery date. I would recommend.
Trustpilot
2 weeks ago
1 week ago