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🛡️ Keep your cat flea-free and fabulous—because your pet deserves the best!
FRONTLINE Plus Flea & Tick Spot Treatment offers fast-acting, waterproof protection that kills fleas, eggs, larvae, lice, and ticks for 30 days with a single monthly application. Trusted by pet owners for over 20 years, it’s designed for cats and kittens 8 weeks and older, providing comprehensive parasite control to keep your feline friend healthy and comfortable.


















| ASIN | B07NF9VV22 |
| Active Ingredients | fipronil and (S)-methoprene |
| Age Range Description | All Life Stages |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #442 in Pet Supplies ( See Top 100 in Pet Supplies ) #4 in Cat Flea Drops |
| Brand | Frontline |
| Brand Name | Frontline |
| Customer Reviews | 4.3 out of 5 stars 51,182 Reviews |
| Dog Breed Size | Small |
| Included Components | Applicator |
| Item Form | Stick |
| Item Type Name | Topical Treatment |
| Item Volume | 8 ml |
| Item Weight | 4.54 g |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer Part Number | 72221 |
| Model Number | 72221 |
| Pet Type | Cat |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Cat |
| UPC | 350604062486 611030624861 |
| Unit Count | 1 Count |
| Volume | 8 ml |
| Warranty Description | If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842. |
J**T
MEWOW THE FLEAS to stay AWAY
I love this stuff, its great and works fine...however it is very important to apply the product monthly as well as correctly. I have thought for years with the Cats I have had, as well as have been told by several vets and vet techs over the years; that the correct way to apply this product is directly on the skin between the shoulder blades. And to be fair to most of the Vets whom have told me that, for the most part I was successful using that method of application. However, as time went on I found this way to apply Frontline more and more difficult as well as it always seem uncomfortable for the Cat. You can use the space between your Cat's shoulder blades as a guide - BUT - the exact proper application spot is actually higher up - at the base of the skull (or as worded inside the package if your Frontline came with the proper instructions `at the base of the neck'). I was very pleasantly surprised that this method was not only much easier, but that there was also no wasted product...I was able to quickly and easily apply the product to each of our 3 cats. I also noticed right away two things. One, each Cat was pretty much comfortable right away and fine as they were before I applied the product - as if I had not even treated them at all. Two, the product was at a spot the cats could not reach even if they wanted to. I don't know why I had never heard of this application method before, as well as why all of the Frontline (and related products) I had purchased in the past said to apply the product directly onto the skin "Between the shoulder blades". This product is great and does work, but it is very important that you apply the product once every 30 days. I would suggest picking a particular date of the month and sticking with that date each and every month. (If you are ever off by a day or two, that is fine - just remember to try and not let it go over 30 days if possible.) Frontline Plus for Cats is not intended to last longer than 30 days, and while it may for some Cats - I personally would not recommend going past the 30 days. If your Cats have worms, this product will keep off the new fleas yes but will do nothing for worms - you should de-worm your Cats first (if needed) and then start with the Frontline about 3 days after de-worming. Indoor Cats can get worms from fleas, even in a very clean home - from time to time some fleas will get in (whether it's on your shoes or from leaving your doors open, etc). Cats usually get worms from when fleas get on them, and then as the cat as it's grooming itself - the cat ingests the fleas (of course the Cat has no idea this will give them worms - they are just cleaning themselves as Cats do). When a Cat eats fleas or other parasites that can get on them from time to time, they can also get other things if left untreated such as Heartworms which are usually fatal. However there is good news! Just apply Frontline once every 30 days and your Cat will stay Flea and parasite free! Any fleas or anything else that may from time to time get onto your Cat will die right away and be of no risk to your Cat. Also over time any residual fleas will eventually die off and your home will be flea - free! However you must apply this product every 30 days year round to ensure that Fleas do not return to your Cat! Preventing your cat from having fleas will in turn not only make you cat much more comfortable, but will also prevent more serious things such as Tapeworms, Roundworms and Heartworms to name just a few things that can originate from your cat ingesting fleas. These more serious conditions for Cats can be prevented with a monthly flea treatment such as Frontline Plus for example. If your cat or home is for some reason very infested with fleas - you have to address that problem first! Remove the cats from the home and use "Flea Bombs" if needed, at least that's how I have always heard them referred to while the proper term is yes "Flea Fogger" or even "Fumigator". You can also use sprays or other like products for your carpet and furniture. Once the home is flea free and your Cat has been treated at the vet for fleas, then make sure to stick with the Frontline every 30 days thereafter. You can also use the Frontline liquid spray to initially kill fleas on the Cat, or a Flea Shampoo. Also keep in mind if your Cat and home are heavily infested with fleas, you should de-worm your cat as well. For most people, de-worming should only be done by or under the direction of a reputable Veterinarian. However if you have owned Cats for many years and know what meds to buy, you can de-worm cats on your own -BUT- only if you are a VERY experienced Cat owner. You can kill your Cat if you give it the wrong type or too much of a de-wormer as de-wormer is a poison (though it's this poison that kills the worms and is perfectly safe when used properly). Frontline helps to keep your cat healthy and is a great preventative medication for your cat. Frontline can and will help keep your Cat healthy and happy for many years to come! Also keep in mind Frontline does not replace periodic checkups or help your Cat in any way if he or she is injured though it will go a very long way in preventing many Cat illnesses and problems related to fleas, ticks, and common parasites. There is more you can do to keep fleas away too, such as treating your yard (unless you have an apartment or condo, etc.) with Pesticide Granules such as Ortho or whatever brand works for you. I am in the Midwest and I would say twice a year is good for the yard treatment, but in South Carolina where I used to live I would have to treat the yard 3 - 4 times a year. If your Cat is outdoor only, keep the Cat inside for 3 -5 days (personally I would say no less than 5 days if possible - a week is more than enough if you want to be extra sure), the same applies for indoor-outdoor cats. This will give the Pesticide time to get into the ground so that it's not toxic to your Cat or small animals such as birds that your Cats may go after. I also use the Riddex Pest repellers....every little bit helps! And of course most importantly of all, apply the Frontline once every 30 days.
K**Y
LOVE!
My family has used Frontline on our cats for as long as I can remember! It's been the most effective treatment for fleas we've ever come across, and we've tried many cheaper ways of ridding out house of fleas. It's cheaper to purchase through Amazon as a 3- or 6-pack than it is to go through your vet. Use with care, though! Some cats, like people, are allergic to components of Frontline. Sort of like the recommendations for hair color on humans, I suggest testing a small amount of Frontline on your pet if this is the first time it's EVER been applied. Rather than creating a large sore for your pet, you're creating small ones. (While this sounds terrible, it's the same way we figure out if children and adults alike are allergic to certain products.) Also, if not placed in the proper spot, the cat is able to lick it, or scratch the spot and then lick their paws, therefore ingesting the product. (This has never happened to my cats, but I had a friend who it did happen to.) PLEASE MAKE SURE YOU'RE APPLYING THE PRODUCT IN THE RIGHT SPOT! See your vet for proper application process if you're not sure. Finally, I suggest using Sevin dust along side Frontline. (NOT ON THE ANIMAL!!) A combination of the two products effectively eliminates fleas safely and quickly (3-10 days). Dust your floors throughout your house! (Contain your pets into one room during this so as to avoid the risk of ingestion. I recommend a tiled room, such as a bathroom or kitchen, where fleas tend not to hide.) Leave on for 3-10 days, until you notice fewer bites and/or itching. BE SURE TO WEAR SHOES AT ALL TIMES, and wash off the shoes after you vacuum the dust up. I also personally recommend vacuuming some into your vacuum bag/container during flea season after you empty. Every little bit helps. (SEVIN DUST CAN ALSO BE SPREAD OUT OVER YOUR YARD, BUT BE SURE TO WATER DOWN YOUR YARD AFTER APPLICATION, AND KEEP YOUR PETS AWAY FROM THE AREA FOR 24-48 HOURS TO ALLOW IT TO SETTLE IN.) These are just some suggestions that we've come across, and that vets have suggested to us in the past. Contact your vet if you have questions, as I'm sure they'll have even more ideas for ridding your family of fleas. :-)
#**E
Fantastic product when it works
Having used Frontline for years during warmer months never had an issue until this year. Whether for the German Sheppard needing a dose of the up to 88 pounds has worked even though he’s a hundred. The cat variety has helped kitties to fluffy cats. This year is the worst flea year I’ve ever seen. Based on research the weather is a perfect storm for these pests to grow in number and hope on pants not just cats. We help feral and stray kitties who have a catio with condos for their enjoyment indoors, and one who goes inside at night and outside during the day. Plus a few indoor who have their own room. The Frontline has helped manage the fleas in the past, but not perfectly this year. I’m not sure why a medium sized four month old short hair kitten, despite having had Frontline still accumulates fleas. We’ve tried bathing it’s Adams high did not work. And Capstar. But these depend on the cat being bit. So she gets a flea comb daily. First, we are being fastidious about cleaning and have no clue, how she is getting new fleas. The other cats haven’t had any comb out. Thought it was her playing with the indoor outdoor friend. But he is clear when combed. We haven’t been able to eliminate them all in the Catio where the feral and stray kitties respite. Upon research learned it could take a few months to break the flea cycle. But we still have them trying to bother two in there, too. Not all, but two in particular. So we use Capstar weekly as needed, to help. Plus flea traps ork well, too. In the winter leaving the window open when it’s in the 30’s and 40’s helps act as a flea bomb. As they die off at that temp. This works for most, not all cats this year. Hoping with different weather the population will die off and the new batch of Frontline will help. Might have been a weak batch maybe? The vet made a comment buying off Amazon might lend to poor quality. Until now that was not the case. We will monitor the problem through the fall and winter. If we have no change will find a new product. We buy quite a bit of this and until now have and perfect success. Though not fond of the poison needed for the warmer months it is imperative to manage the flea potential invasion. We are also looking into alternatives. Like move flea comb use and holistic options. Such as projects like “No-Bite-Me™ Bug Repellent & Itch Relief Cream by SallyeAnder” This stuff works fantastic on me, like while boondock camping. Kept chiggers at bay. Except the area I did not use it covered by my shirt on my midsection. We were in the Tennessee wilderness and not one tick on me or my dog. But the chiggers did there worst to my stomach area. I’ve use this on the kitties and it helped. I’ve gotten some ideas from Veterinary Secrets on YT, too. Sharing my negative experience in case someone else went through this. Hope the information helps with alternatives. And know, sometimes during certain weather patterns fleas can increase. And even attack people off the ground. Encourage doing research. Saving up for sales. Using sub and save for monthly savings options. And know this product itself cannot prevent fleas. It is a multi step process. From a cleaning of the house to adding supplements like flea traps for stragglers that get away. A flea comb. Do not wash the cat for a while following application. Look at directions for full details on this. Or you’ll wash off the product. All in all this is my go to supplement to fight fleas outdoors. And if they hit a ride into the house trying to wreck havoc will treat everyone for several months or until they disappear. This is the first year we have to do this. But I’m glad we have a system set up with options. The sales and sub and save price for this product are helpful. The vet suggesting buying on Amazon compared to from them means the product is potentially inferior when the same product when I’ve not has issues for years makes me feel they wanna upsell. Even though they’re a farm vet and cost less than city vets, still made me think proof is in the outcome. Hope this info helps others find solutions to the flea cycle problems that are a part of life with fur friends
A**H
Works as expected
A few things to address when assessing this product and the other reviews: 1) If you do some research on the internet, you will realize that different flea medications work better in different areas. Advantage did not work for us. Front line does. Just because this product may not work for your pet doesn't mean it's faulty or expired. 2) If your pet already has fleas, this product takes at least three applications before it will start to work effectively. Our cat did have fleas and it took three applications. Fleas are no joke and always take time to get under control. Just because they don't disappear overnight doesn't mean it is faulty or expired. 3) Fleas can become immune. Doesn't mean the product is faulty or expired. 4) It is toxic, obviously. There is a risk your pet could have a serious adverse reaction. It is a pesticide for goodness sake. You are taking a chance and weighing your options. It doesn't make you a terrible person if you have circumstances where your pet having fleas would be terrible - like if you have a newborn or an infant and your pet is hellbent on going outside anyway. So there's all that. With that being said, frontline is the only medication that works for us. We only use it half of the year and start it early enough to be effective by peak flea months, though the product recommends year round applications.
R**S
Apparently Our House Has Become a Small Animal Management Facility
At this point there is definitely a theme forming around here: cats, dogs, pet supplies, flea prevention, repeat. 😄 This has basically become one of those standard household staples when you have multiple cats and don’t want fleas turning the house into a tiny jumping horror movie. We’ve used FRONTLINE products for a long time, and overall this has worked well for routine flea and tick prevention on our cats. The application process is straightforward, and the tubes are easy enough to use without turning the cat into an angry liquid-covered gremlin for the rest of the evening. One thing I especially like is that the doses are pre-measured and simple to apply directly between the shoulders without needing complicated prep. The product also dries reasonably well afterward and hasn’t caused noticeable issues for our cats during normal use. For multi-pet households, staying ahead of fleas becomes way easier than trying to fight a full infestation later after the bugs establish diplomatic control over the property. 😄 The 6-count pack is also convenient because it lasts a decent amount of time and keeps us from constantly needing reorders every few weeks. Overall, this has been another dependable pet-care staple for keeping cats protected and helping maintain household sanity in a house full of animals.
J**Y
Forget it. It doesn't work anymore.
UPDATE 4-5-2015 Screw it. Get Simple Solutions flea and tick spray. It's $8.98 for a large can of it at Wal-Mart. It kills the adults on contact, and does control the eggs and larvae fairly well. It's natural and safe to use around pets, and is said to be able to be sprayed right on them. Well, I use coconut oil on my cats now, instead, but I spray Simple Solutions around my carpet and linoleum about once a day (had a recent flea infestation, so now it's down to the stragglers) and it does great! Here's a link to it here on Amazon: http://www.amazon.com/Simple-Solution-Flea-Tick-Spray/dp/B00TQ8V7F4/ref=sr_1_1?s=pet-supplies&ie=UTF8&qid=1428229091&sr=1-1&keywords=simple+solution+flea UPDATE: 3-19-2015 I purchased this product, in the 3-dose size, again in late January of 2015. It didn't work, and I couldn't figure out why. I was hesitant to come back, but considering that Frontline from Merial has always worked great and been safe, I figured I would try again. I thought, "Maybe it was just a bad batch that I got." Apparently, no, everyone else has been having similar problems. Not only did it not work, but the fleas seemed to get worse instead of better. I have now taken to buying a cheap $10 flea shampoo from PetSmart and using 2 tablespoons of it to 2 1/2 cups of water in a spray bottle that I use on the floor, my bedding, and (every 2 weeks, per instructions), my cat. It's certainly no cure, but it does a better job than the Frontline did at keeping the fleas temporarily at bay. They tend to be attracted to my feet, ankles, and lower legs. I've found that the best protection I have is wearing knee-high office stalkings (the thicker fancy-shmancy kind, not the hosery type). I now realize -why- even men used to wear such things 400 years ago! It was out of NECESSITY. Anyway, they do keep me from getting bit, and when I spray the shampoo spray on my feet, the fleas jump right off. I'm semi-convinced (not completely) that the shampoo is too diluted to cause serious skin harm to me, and I have not shown any sign of an allergic reaction, nor has Sam. When I start to see reviews that Merial has resolved this issue, I will come back to buy. In the meantime, guess I'm stuck with making my own cheap flea-repellent for myself. The brand of shampoo I bought for that was Sentry PurrScriptions Coconut Berry flea and tick shampoo for cats. I'm not a vet or a doctor, so go as both before you try this on yourself or your cat. I'm just winging it, myself. I guess I don't have much other choice. Nothing else seems as effective right now. My Review from Several Years Ago: The Frontline I ordered for my 3 year old male cat, Sam, arrived today! I was prepared with a couple socks and safety pins, a wet washcloth with dishsoap on it (just in case, as dish soap usually gets these kinds of things off of cats and saves their lives most of the time if they have had a life threatening reaction), a scissors, an indellible marking pen (I like it better than stickers 'cause I always lose calendars), and his favorite laser-pointer toy. I read the instructions and went for it. He's been doing great, and there has been no need for the soapy cloth! He hasn't even tried to lick the medication off! He's sort of tried to lick the bottom of the socks around his neck a couple times, but he's not nearly as fussy as he was before. This totally worked out! Saved me the extra cost of going to the vet (who I went to before: she used Frontline on him and then sent me home with 2 months worth more to apply myself). I can highly recommend it for any cat who has previously and successfully been treated with it by a vet and been under their supervision. From what I've been reading online, most cats do fine with it anyway. If testing on a previously untreated cat, either have a vet do it the first time or at least keep that soapy washcloth around (keep a dot of Dawn in one place after getting the cloth wet, and use that dot to remove the medication if your pet has a bad reaction). How do I know that? I had the unfortunate bad experience of using Hartz on Sam about 3 years ago and it POISONED him. He was so close to death that I would try anything - so I went all over the Intertubes looking for answers. The only thing I hadn't tried yet was the soapy washcloth that someone mentioned. I was fortunate enough to have found that in time. Some people found it for their cats, but it was too late, their cats had been exposed for too long. STAY AWAY FROM HARTS! It just basically kills cats -- and it doesn't even do anything to their fleas. Their anti-hairball gel works for Sam just fine, it's never poisoned him, but the flea treatments -- just DON'T DO IT. Use Frontline or kiss your beloved kitty goodbye and have a nice funeral planned. Sam was one of the fortunate (very) few who survived their assault on him. Stores shouldn't carry Hartz flea treatments. Amazon shouldn't either. No one should ever use it. Google it and you'll see for yourself: cats just die from it. ONLY USE FRONTLINE if you love your pets and want them around! PS. I really am sorry that my mentioning that probably hurts a great number of you out there who lost your beloved kitties to Hartz' flea treatment. It's for a good cause, so I'm doing it anyway. My heart goes out to you, and I know full well that, just like me, you had no idea that Hartz' flea treatment would murder your beloved furry friends <3
T**.
Keeps My Barn Cats Protected Month After Month
I’ve been using Frontline Plus on my barn cats, and it’s become part of our regular routine. Because they’re outdoor cats, flea and tick prevention is a must, and this gives me peace of mind knowing they’re protected for a full month. The applicator is simple to use, and once it’s on, I don’t have to think about it again until the next treatment. I appreciate that it also targets flea eggs and larvae, helping break the flea life cycle instead of just treating adult fleas. If you have outdoor or barn cats that spend a lot of time roaming, this is a product I’d recommend keeping on hand. Just be prepared—most cats aren’t thrilled about having it applied, so having a second set of hands can definitely help!
S**R
Excellent price and product
Excellent price and product. More applications per box than we can find locally. Seems to do the job for our cat. Very easy to apply.
Trustpilot
5 days ago
2 months ago